Discovering new ways materials can interface with biology
Research Interests
Polymers
Recent advances in controlled radical polymerizations has provided a platform for the realization of remarkable polymer function and material properties resulting from the ability to control polymer structure, sequence and architecture. The Clemons Lab has interested in pushing the boundaries of these techniques to discover new materials and properties.
Want to know more? Check out some of these recent papers below:
Synthetic copolymer conjugates of docetaxel and in vitro assessment of anticancer efficacy
Biomaterials & Tissue regeneration
The Clemons lab has long focussed on the development of biomaterials for the treatment of disease and injury as well as for tissue regeneration applications. Interests include, polymer nanoparticle drug delivery, supramolecular polymer scaffolds, and multifunctional materials. We are primarily focussed on applications for the treatment of cardiovascular disease, cancer, central nervous system and burn injury.
Want to know more? Check out some of these recent papers below:
Self-Assembling Nanofibers Inhibit Inflammation in a Murine Model of Crohn's Disease-Like Ileitis
Development of novel nanofibers targeted to smoke-injured lungs
Functional soft matter
Nature has evolved to produce remarkably efficient systems to control a diverse range of functions in the body. These often occur from the spatiotemporal control of both physical and chemical signaling events. The Clemons lab is focused on ways we can mimic these functions with programmable active materials that can react to external stimuli or change properties in a reversible fashion.
Want to know more? Check out some of these recent papers below:
Transforming Growth Facto beta-1 Binding by Peptide Amphiphile Hydrogels